Profile of Kazuo Kinoshita

In 1992, Dr. Kazuo Kinoshita graduated from Kyoto University Faculty of Medicine and, after receiving two years of clinical training, entered Graduate School of Medicine at Kyoto University. He joined a laboratory of Professor Tasuku Honjo (Molecular Biology), where he engaged in a study of molecular mechanism of antibody class-switch recombination. After he was promoted to an assistant professor in 1997, he and colleagues cloned a novel gene encoding activation-induced cytidine deaminase (AID), encoded by AICDA. In 2000, they demonstrated that AID is an enzyme essential for class switch and somatic hypermutation of antibody genes. Thereafter, he has been continuing research on AID. Recently, he also started to study erythroblast enucleation.

1986-1992: Kyoto University Faculty of Medicine
1992-1994: clinical training (internal medicine)
1994-1997: Kyoto University Graduate School of Medicine
1997-2003: assistant professor at Kyoto University Graduate School of Medicine
2003-2005: research associate professor at Kyoto University Graduate School of Medicine
2006-2020: staff scientist at Shiga Medical Center Research Institute
2020-2021: senior scientist at Shizuoka General Hospital
2021-present: professor at Shizuoka Graduate University of Public Health

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